MFCD 37501

MFCD 37501 - Names and Identifiers

Name	2',7'-DICHLOROFLUORESCIN DIACETATE
Synonyms	MFCD 37501 diacetyldichlorofluorescein Dichlorofluorescein diacetat 2',7'-DICHLOROFLUORESCIN DIACETATE 2',7'-Dichlorofluorescein diacetat 2',7'-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl diacetate Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,3',6'-bis(acetyloxy)-2',7'-dichloro-
CAS	2044-85-1

MFCD 37501 - Physico-chemical Properties

Molecular Formula	C24H14Cl2O7
Molar Mass	485.27
Density	1.59±0.1 g/cm3(Predicted)
Melting Point	232-234 °C(lit.)
Boling Point	657.9±55.0 °C(Predicted)
Flash Point	>109℃
Solubility	DMSO: soluble
Appearance	Powder or Crystals
Color	Colorless to off-white
BRN	68488
Storage Condition	2-8°C
Use	Uses can be used as an excellent gas phase substitute for underivatized fluorescein, and as a component/substrate for the determination of 2 ', 7'-dichlorofluorescein diacetate to quantify reactive oxygen species (ROS).

MFCD 37501 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns R20/22 - Harmful by inhalation and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	1759
WGK Germany	3
FLUKA BRAND F CODES	3-8-10
HS Code	29329990

MFCD 37501 - Upstream Downstream Industry

Downstream Products

2′,7′-Dichlorodihydrofluorescein Diacetate
2',7'-DICHLOROFLUORESCEIN

MFCD 37501 - Introduction

2 ',7'-DICHLOROFLUORESCIN DIACETATE(2 ',7'-DICHLOROFLUORESCIN DIACETATE) is a fluorescent probe commonly used for the determination of reactive oxygen species in cells and tissues. It is a colorless crystal or powder, soluble in organic solvents such as dimethyl sulfoxide and acetonitrile, but insoluble in water.

The main use of 2 ',7'-DICHLOROFLUORESCIN DIACETATE is to determine the content of reactive oxygen species in cells. It can be used to assess the level of oxidative stress in cells or tissues, to study the effects of oxidative stress on cells and the inhibitory effects of drugs or compounds on oxidative stress. In addition, it can also be used to evaluate apoptosis, cell proliferation and cytotoxicity.

The method for preparing 2 ',7'-DICHLOROFLUORESCIN DIACETATE is generally obtained by reacting fluorescent yellow with anhydrous acetic acid. The specific step is to dissolve the fluorescent yellow in anhydrous acetic acid, then add a certain amount of cuprous chloride as a catalyst, react for a certain period of time, and filter to obtain the product.

Regarding safety information, 2 ',7'-DICHLOROFLUORESCIN DIACETATE needs to be stored in a dark, low-temperature, dry place, and avoid exposure to light and humidity. It is a chemical and care should be taken to avoid contact with the skin and eyes, and to avoid inhalation or ingestion. Appropriate protective equipment, such as lab gloves and safety glasses, should be worn during operation. In case of accidental contact or ingestion, rinse immediately with plenty of water and seek medical help. At the same time, this compound should be used and handled in a safe environment.

Last Update：2024-04-09 21:11:58